Summary: This session introduces core biology concepts, from the central dogma to emerging applications such as phage therapy and genetic circuits. Participants will gain a solid foundation in DNA/RNA structure and function, genome engineering, and circuit design.

Cost for Attendance: $33 (payment links @ door or in advance to @elliot-roth // @thatmre)

Part I Topics & Agenda

• Bio Basics

  • Subtopics: Tree of life, DNA/RNA/proteins, central dogma

• DNA Design & Genome Engineering Methods

  • Subtopics: DNA/gene structure, mutations, vectors, CRISPR, and other DNA modifiers

• Phage Therapeutics

  • Subtopics: Introduction to bacteriophages, the need for phage therapy, future directions

• Genetic Circuits

  • Subtopics: Basic components of genetic circuits, elements required, applications

Slides: https://drive.google.com/drive/u/0/folders/1mhf4eTt9x9P5KzL0g_mSTeXTxZEuZGGj

Recording: https://mit.zoom.us/rec/share/_6KIz4GEzymjMlcqcMTsm3KS0d3ra-SsL2yLeC89JIuGKJw2_cHDJ--3O8K15OqR.iu9c_keqiW_pcBFi

Part I Additional Resources

• Central dogma of molecular biology

  • 🎥  Amoeba Sisters - Protein Synthesis

  • 🎥  DNA Learning Center - The Central Dogma of Biology

  • 🎥  thebiologyprimer - The Central Dogma: DNA to proteins (Long video - 30 mins)

  • 🎥  Thomas Mennella - Lecture 14: The Central Dogma  (Lecture - 60 mins

  • 🎥. Transcription and Translation: From DNA to Protein

• Enzymes

  • 📝 Cleveland Clinic - Enzymes

  • 🎥  Amoeba Sisters - Enzyme Examples, Cofactors/Coenzymes, Inhibitors, and Feedback Inhibition (More in-depth than previous video)

  • 📝 NIH - Essays in Biochemistry - Enzymes: principles and biotechnological applications (Long form essay)

• DNA and RNA (nucleic acids)

  • 🎥 yourgenome - From DNA to protein

  • 🎥 Amoeba Sisters - DNA vs RNA

  • 🎥 Professor Dave Explains - Nucleic Acids: DNA and RNA

  • 🎥 Nucleus Biology - DNA and RNA: Overview of DNA and RNA

  • 📝 Jefferson Computational Medicine Center - DNA and RNA

  • 📝 ThoughtCo - The Differences Between DNA and RNA

• Types of RNA

  • 🎥 Beverly Biology - Types of RNA: (mRNA, tRNA, rRNA)

  • 🎥 Sarah Burke White - RNA Structure and Types of RNA

  • 🎥 Easy Peasy - Structure, Function and Types of RNA (mRNA, tRNA, rRNA, lncRNA, miRNA, siRNA, snoRNA, snRNA, piRNA) (In-depth - 30mins lecture)

  • 🎥 Biology Professor - Regulatory RNA’s: miRNA, siRNA, snRNA, lncRNA (Longer video - 15mins)

  • 🎥 Henrik’s Lab - ncRNAs: all types of non-coding RNA (lncRNA, tRNA, rRNA, snRNA, snoRNA, siRNA, miRNA, piRNA)

  • 📝  ThoughtCo - 4 Types of RNA

📝Microbe Notes - 7 Types of RNA with Structure and Functions